| 货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
|---|---|---|---|---|---|---|
| KR0072 | β-NGF/ NGF/ NGFB (Glu19-Ala241), Human, Recombinant | 10ug |
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| 分子量 | 25 kDa |
|---|---|
| 表观分子量 | 30 kDa |
| 片段与标签 | Glu19-Ala241 |
| 物种 | Human |
| 表达宿主 | E.coli |
产品特性
| 纯度 | ＞95% as determined by reducing SDS-PAGE. |
|---|---|
| 内毒素 | ＜1.0 EU per µg as determined by LAL test. |
| 保存 | Lyophilized Protein should be stored at ＜ -20°C, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at ＜ -20°C for 3 months. |
产品介绍
The precursor form of the Nerve Growth Factor (proNGF) like its mature form is characterized by the cystin knot Motif consisting of three cystine bridges, whereas proneurotrophins and mature neurotrophins elicit opposite biological effects. ProNGF functions preferentially via the complex of pan-neurotrophin Receptor p75 (p75NTR) and vps10p domain-containing Receptor sortilin inducing neuronal apoptosis and contributing to age- and disease-related neurodegeneration.
