| 货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
|---|---|---|---|---|---|---|
| KR0064 | RANK L/ TRANCE/ TNFSF11 (C-6His), Mouse, Recombinant | 10ug |
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| 分子量 | 28.5 kDa |
|---|---|
| 表观分子量 | 30-35 kDa |
| 片段与标签 | Ala73-Asp316 C-6His |
| 生物活性 | Measured by its ability to bind Human TNFRSF11B in functional ELISA. The ED50 for this effect is less than 10 ug/ ml. |
| 物种 | Mouse |
| 表达宿主 | Human Cells |
产品特性
| 纯度 | ＞95% as determined by reducing SDS-PAGE. |
|---|---|
| 内毒素 | ＜1.0 EU per μg as determined by LAL test. |
| 保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 monthshs |
产品介绍
Mouse tumor necrosis factor Ligand superfamily member 11 (Tnfsf11) is a member of the tumor necrosis factor (TNF) Cytokine family. Tnfsf11 is widely expressed in cells including T cells and T cell rich organs, such as thymus and lymph nodes. This Cytokine can bind to TNFRSF11B/ OPG andTNFRSF11A/ RANK. Tnfsf11 is involved in a number of fundamental biological processes such as acting as regulator of interactions between T-cells and dendritic cells, the regulation of the T-cell-dependent immune response and enhancing bone-resorption in humoral hypercalcemia of malignancy. It augments the ability of dendritic cells to stimulate naive T-cell proliferation.
