| 货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
|---|---|---|---|---|---|---|
| KR0219 | TNF-R2/ CD120b/ TNFRSF1B (C-mFc), Human, Recombinant | 10ug |
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| 分子量 | 46.5 kDa |
|---|---|
| 表观分子量 | 60 kDa |
| 片段与标签 | Pro24-Thr206 |
| 物种 | Human |
| 表达宿主 | Human Cells |
产品特性
| 纯度 | ＞95% as determined by reducing SDS-PAGE. |
|---|---|
| 内毒素 | ＜1.0 EU per µg as determined by LAL test. |
| 保存 | Lyophilized Protein should be stored at ＜ -20°C, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at ＜ -20°C for 3 months. |
产品介绍
Tumor necrosis factor Receptor superfamily member 1B (TNFRSF1B) is a member of the tumor necrosisfactor Receptor superfamily. Human TNF RII contains four cysteinerich repeats in its ECD, which shares 58%and 56% amino acid sequence identity with the mouse and rat orthologs, respectively.TNF RII is expressedpredominantly on cells of the hematopoietic lineage, such as T and natural killer cells, as well as onendothelial cells, microglia, astrocytes,neurons, oligodendrocytes, cardiac myocytes, thymocytes, andmesenchymal stem cells.TNF RII binds to the membranebound forms of TNFα and Lymphotoxinα/ TNFβ;soluble TNF is thought to signal predominately through TNF RI.Soluble TNF RII is believed to inhibit TNFbiological activity by binding TNF thereby preventing it from activating membrane TNF Receptors.
