| 货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
|---|---|---|---|---|---|---|
| KR0020 | IGF-I/ IGF1/ MGF (4-70), Human, Recombinant | 10ug |
+
-
|
|
| 分子量 | 7.3 kDa |
|---|---|
| 表观分子量 | 9 kDa |
| 片段与标签 | Thr52-Ala118 |
| 生物活性 | Measured by its ability to induce NFKB reporter gene expression in HEK 293 cell line. Measured in a serum-free cell proliferation assay using MCF‑7 human breast cancer cellsThe ED50 for this effect is less than 200 ng/ ml. |
| 物种 | Human |
| 表达宿主 | E.coli |
产品特性
| 纯度 | ＞95% as determined by reducing SDS-PAGE. |
|---|---|
| 内毒素 | ＜0.5 EU per µg as determined by LAL test. |
| 保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks.＜br/ >Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days.＜br/ >Aliquots of reconstituted samples are stable at < -20℃ for 3 monthshs |
产品介绍
Insulin-Like Growth Factor I (IGF1) belongs to the family of Insulin-Like Growth Factors that are structurally homologous to proInsulin. Mature IGFs are generated by proteolytic processing of inactive precursor Protein containing N-terminal and C-terminal propeptide regions. Mature human IGF-I consisting of 70 amino acids with 94% identity with mouse IGF1 and exhibits cross-species activity. IGF1 binds IGF-1R, IGF-2R, and the Insulin Receptor and plays a key role in cell cycle progression, cell proliferation and tumor progression. IGF1 expression is regulated by growth hormone.
