| 货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
|---|---|---|---|---|---|---|
| KR0176 | IL-16/ LCF, Human, Recombinant | 10ug |
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| 分子量 | 13.4 kDa |
|---|---|
| 表观分子量 | 18 kDa |
| 片段与标签 | Met1-Ser130 |
| 生物活性 | Measured by its to chemoattract human CD4+ T-lymphocytes using a concentration range of 10.0-100.0 ng/ mlThe ED50 for this effect is typically 0.1 ug/ mL. |
| 物种 | Human |
| 表达宿主 | E.coli |
产品特性
| 纯度 | ＞95% as determined by reducing SDS-PAGE. |
|---|---|
| 内毒素 | ＜1.0 EU per µg as determined by LAL test. |
| 保存 | Lyophilized Protein should be stored at ＜ -20℃, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months |
产品介绍
Interleukin-16 (IL-16) is a CD8+ T cell-Derived Cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, human IL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that Receptor cross-linking may be required for activity. IL-16 also induces expression of IL-2 Receptor (IL-2R) and MHC class II molecules on CD4+ T cells. Human and murine IL-16 show significant cross-species reactivity.
