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IL-1α/ IL1F1, Human, Recombinant

  • 货号:KR0048
货号 产品名称 规格 库存 价格 数量 购买
KR0048 IL-1α/ IL1F1, Human, Recombinant 10ug

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分子量 18 kDa
表观分子量 17 kDa
片段与标签 Ser113-Ala271
生物活性 Measured by its ability to induce NFKB reporter gene expression in HEK 293 cell line.The ED50 for this effect is less than 50 pg/ mL.
物种 Human
表达宿主 E.coli

 

产品特性

 

纯度 >95% as determined by reducing SDS-PAGE.
内毒素 <1.0 EU per µg as determined by LAL test.
保存 Lyophilized Protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.

 

产品介绍

Interleukin-1 alpha (IL1α) is a Cytokine member of the Interleukin-1 family. IL-1 consists of two distinct forms: IL1α and IL1β that recognize the same cell surface Receptors but are distinct Proteins with approximately 25% amino acid sequence identity. IL1α is constitutively produced by epithelial cells and plays an essential role in maintenance of skin barrier function. Upon stimulation, a wide variety of cells including osteoblasts, monocytes, macrophages can be induced to express IL1α. IL1α possesses a wide range of metabolic, physiological, haematopoietic activities, and is critically involved in the regulation of the immune responses and inflammatory responses.

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