| 货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
|---|---|---|---|---|---|---|
| KR0109 | ACVR2A (C-6His), Human, Recombinant | 10ug |
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| 分子量 | 14.35 kDa |
|---|---|
| 表观分子量 | 32 kDa |
| 片段与标签 | Ala20-Pro134 |
| 物种 | Human |
| 表达宿主 | Human Cells |
产品特性
| 纯度 | ＞95% as determined by reducing SDS-PAGE. |
|---|---|
| 内毒素 | ＜1.0 EU per µg as determined by LAL test. |
| 保存 | Lyophilized Protein should be stored at ＜ -20°C, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at ＜ -20°C for 3 months. |
产品介绍
Activin Receptor Type-2A is a Protein that in humans is encoded by the ACVR2A gene. ACVR2A is an activintype 2 Receptor. This gene encodes activin A type II Receptor. Activins are dimeric growth anddifferentiation factors which belong to the transforming Growth Factor-beta (TGF-beta) superfamily ofstructurally related signaling Proteins. Activins signal through a heteromeric complex of Receptor serinekinases which include at least two type I (I and IB) and two type II (II and IIB) Receptors. These Receptors areall transmembrane Proteins, composed of a Ligand-binding extracellular domain with cysteine-rich region, atransmembrane domain, and a cytoplasmic domain with predicted serine/ threonine specificity. Type IReceptors are essential for signaling; and type II Receptors are required for binding Ligands and forexpression of type I Receptors. Type I and II Receptors form a stable complex after Ligand binding, resultingin phosphorylation of type I Receptors by type II Receptors. Type II Receptors are considered to beconstitutively active kinases.
