| 货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
|---|---|---|---|---|---|---|
| KR0160 | IFN-λ1/ IL-29 (C-10His), Human, Recombinant | 10ug |
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| 分子量 | 21.4 kDa |
|---|---|
| 表观分子量 | 32 kDa |
| 片段与标签 | Gly20-Thr200 |
| 物种 | Human |
| 表达宿主 | Human Cells |
产品特性
| 纯度 | ＞95% as determined by reducing SDS-PAGE. |
|---|---|
| 内毒素 | ＜1.0 EU per µg as determined by LAL test. |
| 保存 | Lyophilized Protein should be stored at ＜ -20℃, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months |
产品介绍
Interleukin-29 (IL-29) is a secreted Protein which belongs to the IL-28/ IL-29 family. IL-29 is a Cytokine with immunomodulatory activity. IL-29 is highly similar in amino acid sequence to the IL-28. IL-28 and IL-29 are induced by viral infection and showed antiviral activity. IL-28 and IL-29 interacted with a heterodimeric class II Cytokine Receptor that consisted of IL-10 Receptor beta (IL-10R beta) and an orphan class II Receptor chain, designated IL-28R alpha. IL-29 plays an important role in host defenses against microbes and its gene is highly upregulated in cells infected with viruses. IL-29 may play a role in antiviral immunity. IL-29 up-regulates MHC class I antigen expression. It is a Ligand for the heterodimeric class II Cytokine Receptor composed of IL10RB and IL28RA. The Ligand/ Receptor complex seems to signal through the Jak-STAT pathway.
