| 货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
|---|---|---|---|---|---|---|
| KR0222 | TNFR2/ TNFRSF1B/ CD120b (C-6His), Human, Recombinant | 10ug |
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| 分子量 | 26.2 kDa |
|---|---|
| 表观分子量 | 40 kDa |
| 片段与标签 | Leu23-Asp257 |
| 生物活性 | Measured by its ability to inhibit TNFa-mediated cytotoxicity using L‑929 mouse fibroblast cells treated with TNFaThe ED50 for this effect is less than 0.6 µg/ mL. |
| 物种 | Human |
| 表达宿主 | Human Cells |
产品特性
| 纯度 | ＞95% as determined by reducing SDS-PAGE. |
|---|---|
| 内毒素 | ＜1.0 EU per µg as determined by LAL test. |
| 保存 | Lyophilized Protein should be stored at ＜ -20℃, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months |
产品介绍
Tumor necrosis factor Receptor superfamily member 1B is a 461 amino acids Protein that belongs to the TNFR (tumor necrosis factor Receptor) superfamily characterized by cysteine-rich extracellular domains. It contains 4 TNFR-Cys repeats. TNFRII is expressed in fetal brain. TNFRII is strongly expressed at the cartilage-pannus junction, and plays a major role in a subset of families with multiple cases of rheumatoid arthritis (RA). This Receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.
