| 货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
|---|---|---|---|---|---|---|
| KR0114 | MCP-1/ CCL2, Human, Recombinant | 10ug |
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| 分子量 | 8.7 kDa |
|---|---|
| 表观分子量 | 13 kDa |
| 片段与标签 | Gln24-Thr99 |
| 生物活性 | Testing in progress |
| 物种 | Human |
| 表达宿主 | E.coli |
产品特性
| 纯度 | ＞95% as determined by reducing SDS-PAGE. |
|---|---|
| 内毒素 | ＜1.0 EU per µg as determined by LAL test. |
| 保存 | Lyophilized Protein should be stored at ＜ -20℃, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months |
产品介绍
The Chemokine (C-C Motif) Ligand 2 (CCL2), also known as monocyte chemoattractant Protein (MCP)-1 and small inducible Cytokine A2 (SCYA2)), is a small Cytokine that belongs to the CC Chemokine family responsible for monocyte attraction. Its cognate Receptor, CCR2, play a critical role in regulating nociceptive processes during neuropathic pain. Both CCL2 and CCR2 are implicated in induction of autoimmunity. CCL2 recruits monocytes, memory T cells, and dendritic cells to the sites of inflammation produced by either tissue injury or infection. Recently research also showed that CCL2 might be useful as a biomarker of fibrosis as well as a target for therapeutic intervention.
