| 货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
|---|---|---|---|---|---|---|
| KR0229 | Exodus-2/ CCL21a, Mouse, Recombinant | 10ug |
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| 分子量 | 12.0 kDa |
|---|---|
| 表观分子量 | 16 kDa |
| 片段与标签 | Ser24-Gly133 |
| 生物活性 | Testing in progress |
| 物种 | Mouse |
| 表达宿主 | E.coli |
产品特性
| 纯度 | ＞95% as determined by reducing SDS-PAGE. |
|---|---|
| 内毒素 | ＜1.0 EU per μg as determined by LAL test. |
| 保存 | Lyophilized Protein should be stored at ＜ -20℃, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months |
产品介绍
C-C Motif Chemokine 21a (CCL21a) is a small secreted Cytokine that belongs to the intercrine beta (CC Chemokine) family. Mouse CCL21 cDNA encodes a 133 amino acid residue Protein with a 23 residue signal peptide that is cleaved to generate the 110 residue mature Protein. Mouse CCL21 has three forms while CCL21a has Ser-65. CCL21 elicits its effects by binding to a cell surface Chemokine Receptor known as CCR7 and CXCR3. Mouse CCL21 inhibits hemopoiesis and stimulates chemotaxis. It has chemotactic function in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Mouse CCL21 shows preferential activity towards naive T-cells and may play a role in mediating homing of lymphocytes to secondary lymphoid organs.
