| 货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
|---|---|---|---|---|---|---|
| KR0094 | TGFB1/ TGFβ1/ TGF-β1, Human, Recombinant | 10ug |
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| 分子量 | 12.8 kDa |
|---|---|
| 表观分子量 | 13 kDa |
| 片段与标签 | Ala279-Ser390 |
| 生物活性 | Testing in progress |
| 物种 | Human |
| 表达宿主 | Human Cells |
产品特性
| 纯度 | ＞95% as determined by reducing SDS-PAGE. |
|---|---|
| 内毒素 | ＜1.0 EU per µg as determined by LAL test. |
| 保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks |
产品介绍
Transforming Growth Factor β-1 (TGFβ-1) is a secreted Protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGFβ-1 peptide. TGFβ-1 may also form heterodimers with other TGFβ family members. It has been found that TGFβ-1 is frequently upregulated in tumor cells. Mutations in this gene results in Camurati-Engelmann disease.
