| 货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
|---|---|---|---|---|---|---|
| KR0190 | IL-28B/ IFN-λ3 (C-6His), Human, Recombinant | 10ug |
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| 分子量 | 20.7 kDa |
|---|---|
| 表观分子量 | 19 kDa |
| 片段与标签 | Val22-Val196 C-6His |
| 生物活性 | Measured by its ability to binding IL10RB used funtional ELISA. The ED50 for this effect is less than 10 ug/ ml. |
| 物种 | Human |
| 表达宿主 | Human Cells |
产品特性
| 纯度 | ＞95% as determined by reducing SDS-PAGE. |
|---|---|
| 内毒素 | ＜1.0 EU per µg as determined by LAL test. |
| 保存 | Lyophilized Protein should be stored at ＜ -20℃, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months |
产品介绍
Interleukin-28B, also known as Cytokine Zcyto22, Interferon lambda-3, Interferon lambda-4, IFNL3, IFNL4, ZCYTO22 and IL28B, is a secreted Cytokine which belongs to the IL-28/ IL-29 family. IL-28 has also been shown to play a role in the adaptive immune response. IL28B has immunomodulatory activity and up-regulates MHC class I antigen expression. IL28B displays potent antiviral activity and antitumor activity. In addition, IL28B is a Ligand for the heterodimeric class II Cytokine Receptor composed of IL10RB and IL28RA. The Ligand/ Receptor complex seems to signal through the Jak-STAT pathway.
