| 货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
|---|---|---|---|---|---|---|
| KR0168 | ST2/ IL1RL1, Human, Recombinant | 10ug |
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| 分子量 | 36.0 kDa |
|---|---|
| 表观分子量 | 60 kDa |
| 片段与标签 | Lys19-Phe328 C-6His |
| 生物活性 | Measured by its binding ability in a functional ELISA. 2. Immobilized recombinant human IL33 at 10 μg/ mL (100 μl/ well) can bind biotinylated human IL1RL1 (isoform A) with a linear range of 0.032-8 μg/ ml. |
| 物种 | Human |
| 表达宿主 | Human Cells |
产品特性
| 纯度 | ＞95% as determined by reducing SDS-PAGE. |
|---|---|
| 内毒素 | ＜1.0 EU per µg as determined by LAL test. |
| 保存 | Lyophilized Protein should be stored at ＜ -20℃, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months |
产品介绍
Interleukin 1 Receptor-like 1 (IL1RL1) is a member of the Interleukin-1 Receptor family, Contains 3 Ig-like C2-type domains and 1 TIR domain. It is highly expressed in kidney, lung, placenta, stomach, skeletal muscle, colon and small intestine. IL1RL1 is a Receptor for Interleukin-33, its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ ERK1 and/ or MAPK1/ ERK2, MAPK14, and MAPK8. IL1RL1 may possibly be involved in helper T-cell function. Soluble IL1RL1 also acts as a negative regulator of Th2 Cytokine production, it directly implicated in the progression of cardiac disease.
