| 货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
|---|---|---|---|---|---|---|
| KR0082 | IL-7, Human, Recombinant | 10ug |
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| 分子量 | 17.5 kDa |
|---|---|
| 表观分子量 | 18 kDa |
| 片段与标签 | Asp26-His177 |
| 生物活性 | Measured in a cell proliferation assay using PHA-activated human peripheral blood lymphocytes (PBL).The ED50 for this effect is less than 0.4 ng/ ml. |
| 物种 | Human |
| 表达宿主 | E.coli |
产品特性
| 纯度 | ＞95% as determined by reducing SDS-PAGE. |
|---|---|
| 内毒素 | ＜1.0 EU per µg as determined by LAL test. |
| 保存 | Lyophilized Protein should be stored at ＜ -20°C, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at ＜ -20°C for 3 months. |
产品介绍
Human Interleukin 7 (IL-7) is a potent lymphoid cell Growth Factor stimulating the proliferation of lymphoid progenitors. IL7 can associate with the hepatocyte Growth Factor (HGF) to form a hybrid Cytokine that functions as a pre-pro-B cell growth-stimulating factor. Human IL7 cDNA encodes a 177 amino acid precursor Protein containing a 25 amino acid signal peptide and a 152 amino acid mature Protein. Human and mouse IL7 share 65% sequence identity in the mature region and both exhibit cross-species activity. IL-7 signals via IL-7 Receptor (IL7R) activating multiple pathways including JaK/ STAT and PI3K/ AKT, which regulate lymphocyte survival, glucose uptake, proliferation, and differentiation. IL-7 is also associated with cytoplasmic IL2-R gamma for signal transduction.
