| 货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
|---|---|---|---|---|---|---|
| KR0052 | IL-15, Human, Recombinant | 10ug |
+
-
|
|
| 分子量 | 12.5 kDa |
|---|---|
| 表观分子量 | 12 kDa |
| 片段与标签 | Asn49-Ser162 |
| 生物活性 | Measured in a cell proliferation assay using CTLL‑2 mouse cytotoxic T cellsThe ED50 for this effect is less than 0.5 ng/ ml. |
| 物种 | Human |
| 表达宿主 | E.coli |
产品特性
| 纯度 | ＞95% as determined by reducing SDS-PAGE. |
|---|---|
| 内毒素 | ＜1.0 EU per µg as determined by LAL test. |
| 保存 | Lyophilized Protein should be stored at ＜ -20℃, though stable at room temperature for 3 weeks.＜br/ >Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days.＜br/ >Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months |
产品介绍
Human Interleukin 15 (IL-15) is a Cytokine that regulates T cell and natural killer cell activation and proliferation. IL-15 binds to the alpha subunit of the IL15 Receptor (IL-15RA) with high affinity. IL-15 also binds to the beta and gamma chains of the IL-2 Receptor, but not the alpha subunit of the IL2 Receptor. IL-15 is structurally and functionally related to IL-2. Both Cytokines share some subunits of Receptors, allowing them to compete for and negatively regulate each other's activity. The number of CD8+ memory T cells is controlled by a balance between IL-15 and IL-2. Despite their many overlapping functional properties, IL-2 and IL-15 are, in fact, quite distinct players in the immune system. IL-15 is constitutively expressed by a wide variety of cell types and tissues, including monocytes, macrophages and DCs. Mature Human IL-15 shares 70% amino acid sequence identity with Mouse and Rat IL-15.
