| 货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
|---|---|---|---|---|---|---|
| KR0029 | IL-2/ IL2, Mouse, Recombinant | 10ug |
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| 分子量 | 17.4 kDa |
|---|---|
| 表观分子量 | 17 kDa |
| 片段与标签 | Ala21-Gln169 |
| 生物活性 | Measured in a cell proliferation assay using CTLL‑2 mouse cytotoxic T cellsThe ED50 for this effect is less than 0.5 ng/ ml. |
| 物种 | Mouse |
| 表达宿主 | E.coli |
产品特性
| 纯度 | ＞95% as determined by reducing SDS-PAGE. |
|---|---|
| 内毒素 | ＜1.0 EU per µg as determined by LAL test. |
| 保存 | Lyophilized Protein should be stored at ＜ -20℃, though stable at room temperature for 3 weeks.Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at ＜ -20℃ for 3 months |
产品介绍
Interleukin 2 (IL 2), also termed T-cell Growth Factor, is a member of the Cytokine family which includes IL-4, IL-7, IL-9, IL-15 and IL-21. Each member of this family has a four alpha helix bundle. IL-2 signals through the IL-2 Receptor, a complex consisting of tree subunits, termed alpha, beta and gamma. The IL-2 R gamma is shared by Cytokine Receptors of all members of Cytokine family. Mature mouse IL-2 shares 56% and 73% aa sequence identity with human and rat IL-2, respectively. IL-2 is produced by CD4+ T cell, CD8+ T cells, gamma δ T cells, B cells, dendritic cells and eosinophils, and plays a vital role in key function of the immune system, tolerance and immunity, primarily via its potent stimulatory activity for T cells.Thus, IL-2 may be a key Cytokine in the natural suppression of autoimmunity.
