| 货号 | 产品名称 | 规格 | 库存 | 价格 | 数量 | 购买 |
|---|---|---|---|---|---|---|
| KR0003 | IFNGR1/ CD119, Human, Recombinant | 10ug |
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| 分子量 | 28.7 kDa |
|---|---|
| 表观分子量 | 40-50 kDa |
| 片段与标签 | Glu18-Ser245 C-6His |
| 生物活性 | Measured by its ability to inhibit rhIFNγ mediated protection of WISH cells infected with vesicular stomatitis virus (VSV).The ED50 for this effect is typically 2-8 μg/ mL. |
| 物种 | Human |
| 表达宿主 | Human Cells |
产品特性
| 纯度 | ＞90% as determined by reducing SDS-PAGE. |
|---|---|
| 内毒素 | ＜1.0 EU per µg as determined by LAL test. |
| 保存 | Store at ＜ -20℃, stable for 6 monthshs after receipt.Please minimize freeze-thaw cycles |
产品介绍
Interferon gamma Receptor 1 (IFNGR1) encoded by the IFNGR1 gene, is a single-pass type 1 membrane Protein which belongs to the type II Cytokine Receptor family. IFNGR1 is phosphorylated at Ser/ Thr residues after translation. IFNGR1 is a Receptor for interferon gamma, two Receptors bind one interferon gama dimer. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.
