人直肠成纤维细胞

人直肠成纤维细胞 货号：KL-YCP042
1、细胞简介：
The human rectum is located in the lower gastrointestinal tract and functions as a temporary storage site for fecal material. Rectal fibroblasts are important structural components of the rectum and are implicated in a number of diseases including ulcerative colitis, Crohn’s disease, and rectal cancer. Fibroblasts are mesenchymal cells derived from the embryonic mesoderm. The main functions of fibroblasts are to maintain the structural integrity of connective tissue and to aid in tissue repair and remodeling [1, 2]. Studies have shown that functional changes to human rectal fibroblasts (HRecF) can impair wound healing and affect epithelial cell proliferation in ulcerative colitis patients [3]. In Crohn’s disease, HRecF respond to intestinal inflammation by proliferating abnormally, which leads to fibrotic scarring. Primary HRecF can be used to study the pathophysiology of rectal cancer, ulcerative colitis, and Crohn’s disease and to help develop therapies for these diseases.
2,、细胞图片：